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Mania and Testosterone

The androgen hormone testosterone is secreted in the adrenal glands and ovaries in women and in the adrenal glands and testes in men.  The hormone is closely related to optimal sexual performance in both men and women.  Bipolar disorder, which is associated with depression and mania, may worsen due to an imbalance in testosterone levels. Low testosterone can cause clinical depression.  Testosterone may not be a direct cause of the chemical imbalance underlying depression.  Low levels of this hormone, however, gives rise to a decreased sex drive, irritability and a lack of energy.  These negative mental and physical factors may lead to an increased breakdown of serotonin in the brain, a state directly linked to depression. High testosterone levels, on the other...

The androgen hormone testoster...

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