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Neuroplasticity and THC

The role of neuroplasticity (i.e. the way that the brain develops over time) is widely recognized in healthy development, learning, memory, and recovery from brain damage.  It occurs in response to experiences and consists of neurogenesis (neuron creation) and neuro-degeneration (neuron death).  According to this study from Israel performed by Sackler Faculty of Medicine, there are a number of ways in which neuroplasticity is measured. Extracellular-signal-regulated kinases (ERKs) are protein enzymes that modify other proteins.  These protein enzymes are involved in regulating the processes involved with cell differentiation.  Researchers observed the amount of ERKs in the brain and found long-lasting differences within the hippocampus (involved in memory integration), frontal cortex (involved in planning, judging, personality, etc.), and cerebellum (involved in regulating balance, attention, etc.). cAMP response element-binding protein (CREB) is a protein that binds to the cAMP DNA sequence. It is...

The role of neuroplasticity (i...

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Caudate Nucleus

caudate nucleus

"Anytime you have a change in behavior you have a change in the brain," said UCLA psychiatrist Dr. Lewis Baxter.  "Behavior therapy and drugs appear to rearrange brain circuitry in the same way." Baxter and his colleagues studied the brains of obsessive-compulsive patients with PET (positron emission tomography) scans, a technique that measures the activity of cells in different areas of the brain.  They found that an area called the caudate nucleus was overactive in these patients. The caudate nucleus acts as a gate-keeper that prevents unwanted thoughts from establishing self-reinforcing circuits in the brain.  Like a record stuck in the same groove, unwanted thoughts keep repeating themselves and drive compulsive behavior. Fluoxetine (Prozac) is highly effective in curbing unwanted thoughts through a mechanism...

"Anytime you have a change in ...

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