You’ve heard the story: Fluoxetine/Prozac increases serotonin levels. But what difference does that make? What happens after serotonin increases? That’s a good question. Here’s the current working answer: it looks like antidepressants, and exercise, and other antidepressant approaches including even ECT (electroconvulsive therapy), all cause brain cells to start to feed themselves again. Huh? That’s right, these effective treatments all cause the brain to make a protein that helps cells grow and make connections to neighbors.
Brain Derived Neurotrophic Factor (BDNF)
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